Our consortium meeting took place on August 4–9, 2025 at Goethe University Frankfurt, Germany, focusing on identifying and quantifying RNA chemical modifications.

Parallel breakout sessions covered non–mass spectrometry direct RNA sequencing methods, biological implications, and data storage. 

1st Human RNome Project Workshop

Key Outcomes

  • Built momentum for sequencing RNA with all chemical modifications 

  • Established a harmonized protocol for ribonucleoside identification and quantitation 

  • Launched a collaborative project to draft human RNome sequences as a benchmark 

  • Formed an early-career scientist group led by Rami Bechara, Bennett Henzeler, Rebekah Penrice-Randal.

Summary of Breakout Sessions

A summary of the breakout sessions from our first workshop, prepared by Rami Bechara, Bennett Henzeler, and Rebekah Penrice-Randal.